igsr/1000 Genomes 30x

The 1000 Genomes Project produced high-coverage (30x) whole genome sequencing data for 3,202 samples from 26 populations across 5 continents. This dataset is one of the most widely used references for population genetics and serves as a foundational imputation panel.

What’s included

• CRAM alignments for all 3,202 samples against GRCh38
• Joint-called VCFs with SNPs, indels, and structural variants
• Population metadata including super-population and sub-population labels
• Phased haplotypes suitable for imputation reference panels

Use cases

This dataset serves as the gold-standard reference for population allele frequencies, imputation panels, and benchmarking variant callers. It is commonly used in GWAS, pharmacogenomics, and ancestry estimation.